Left ventricular diastolic dysfunction: Early diastolic relaxation and late diastolic compliance

Diastolic heart failure, diastolic left ventricular dysfunction and exercise intolerance.

The phenomenon of “diastolic heart failure” is rightly receiving greater attention (1–4); community-based studies such as those in Framingham (5) and Olmsted County (6) show that up to 50% of older persons with heart failure do not have impaired left ventricular (LV) systolic function to account for this, and that the condition is usually associated with LV hypertrophy and is preceded by elevat...

Early diastolic filling dynamics in diastolic dysfunction

BACKGROUND The aim of the study was to determine the relationship between the rate of peak early mitral inflow velocity and the peak early diastolic mitral annular tissue velocities in normal controls and to compare them with subjects with diastolic dysfunction. METHODS The relationship between early passive diastolic transmitral flow and peak early mitral annular velocity in the normal and i...

Diastolic Left Ventricular Dysfunction A Clinical Appraisal

Objective: In dilated cardiomyopathy and in athlete’s heart, progressive LV dilatation is accompanied by rightward displacement of thediastolic LV pressure–volume relation. In dilated cardiomyopathy, an increase in diastolic LV stiffness can limit this rightwarddisplacement thereby decreasing LV systolic performance. Because nitric oxide (NO) reduces diastolic LV stiffness, the present ...

Left ventricular diastolic dysfunction in atrial fibrillation

Left Ventricular Diastolic Dysfunction in Peritoneal Dialysis

Left ventricular diastolic dysfunction (LVDD) is common among patients undergoing peritoneal dialysis (PD). We examined the relationship between LVDD, major adverse cardiovascular events (MACE), and mortality in PD patients. A total of 149 patients undergoing PD with preserved left ventricular systolic function were included and followed for 3.5 years. LVDD was diagnosed (according to the Europ...